Stability of Stabilized 99mTc-D,L-HMPAO Stored in Vials and Syringes

Stability of Bortezomib 2.5 mg/mL in Vials and Syringes Stored at 4°C and Room Temperature (23°C).

BACKGROUND Solutions of bortezomib 1.0 mg/mL for IV administration are reportedly stable for up to 42 days. Recent publications have reported that the safety profile of bortezomib is better with subcutaneous administration than with IV administration. OBJECTIVE To evaluate the stability of higher-concentration bortezomib solutions for subcutaneous administration (i.e., 2.5 mg/mL in 0.9% sodiu...

Stability of pantoprazole sodium in glass vials, polyvinyl chloride minibags, and polypropylene syringes.

BACKGROUND Pantoprazole sodium, a proton-pump inhibitor, is approved for the short-term treatment of several types of ulcer, Zollinger-Ellison syndrome, and gastroesophageal reflux disease. OBJECTIVE To determine the physical compatibility and chemical stability of ethylenediaminetetra-acetic acid (EDTA)-free pantoprazole in glass vials, polypropylene syringes, and polyvinylchloride (PVC) min...

Adsorption of (99m)Tc-radiopharmaceuticals onto injection vials and syringes.

UNLABELLED Many groups have reported the adsorption or retention of (99m)Tc-radiopharmaceuticals on injection vials and disposable plastic syringes. Such an enormously high loss of radioactivity would result in poor images, radiation exposure, waste, and economic burdens. We therefore decided to investigate the extent of adsorption or retention of several (99m)Tc-radiopharmaceuticals on injecti...

Are leukocytes labeled with stabilized 99mTc-HMPAO becoming activated during labeling?

Pre-testing for delamination in pharmaceutical vials | Ampules, vials, syringes and tubes | Healthcare Packaging

By 2013, world pharmaceutical packaging demand is projected to increase to $62.3 billion dollars, increasing from last year’s $45.9 billion. Packaging is a vital and critical step in the drug development process, and after spending up to 10 years or more and millions of dollars developing a product, it’s the last thing manufacturers should overlook. Packaging should be tested just as rigorously...